Randomized Assessment of Rapid Endovascular Treatment of Ischemic Stroke

Mayank Goyal et al. · PI MIchael D Hill, MD MSc FRCPC

Primary endpoint

Shift in the mRS score, defined by a proportional odds model.

Population

Ischemic Stroke; n=316

doi:10.1056/NEJMoa1414905

Historical

Current

Future

3 noemes

Historical

1 noeme

Published findings from this trial. Vote whether the expert body still believes each noeme stands given current evidence.

The ESCAPE trial's stated primary conclusion — Rapid endovascular treatment improves functional outcomes in proximal anterior-circulation stroke. — replicates in independent cohorts.

neurointerventional

Current

1 noeme

Noemes tracking active replication, subgroup analysis, or long-term follow-up. Vote on the likelihood the original effect holds.

Recent follow-up analyses of ESCAPE are confirming the original effect size in real-world data.

neurointerventional

Future

1 noeme

Open forecast horizons tied to this trial. Vote your probability that each resolves TRUE by the declared horizon.

By 2028, median door-to-puncture time at thrombectomy centers will meet or beat the ESCAPE benchmark of ≤60 minutes.

neurointerventional

71%

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