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Trial · NCT01804355

Noeme · 03zu4nqa

Forecast horizon — calibration-scored at resolution.

By 2028, the MR CLEAN effect size (~13% absolute mRS 0–2 improvement) will be confirmed within ±3 points in pooled real-world US registries.

TL;DR · AI-generated

tldr@v2.0.0
semanticscholar.org

In patients with acute ischemic stroke caused by a proximal intracranial occlusion of the anterior circulation, intraarterial treatment administered within 6 hours after stroke onset was effective and safe.

Your probability this resolves TRUE

Consensus 71%

0% (impossible)

50%

100% (certain)

25
50
75

Proper-scoring-rule preview

If TRUE: Brier 0.250 · log 0.69 · +8 rep
If FALSE: Brier 0.250 · log 0.69 · -1 rep
Kelly 25.0% ≈ 250 rep
vs. consensus: 0.15 bits

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Evidence stream

2 events · 1 snapshot

posterior drift

71% → 71% (0pp · 1 point)

posterior drift: 71% → 71%
neutral

Registry data

NCT01804355

Apr 18, 2026

supports

Peer-reviewed paper

+21pp

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Source publication

A Randomized Trial of Intraarterial Treatment for Acute Ischemic Stroke

Olvert A. Berkhemer et al. · New England Journal of Medicine · 2015

6.5k citations
143 influential
FWCI 405.7 · Landmark
OA · bronze
56 authors · 63% ORCID

· openalex W2139621750 · s2 93d703fd