Active replication — ongoing trial, registry, or meta-analysis.
Recent follow-up analyses of MR CLEAN are confirming the original effect size in real-world data.
TL;DR · AI-generated
In patients with acute ischemic stroke caused by a proximal intracranial occlusion of the anterior circulation, intraarterial treatment administered within 6 hours after stroke onset was effective and safe.
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Evidence stream
2 events · 1 snapshot
posterior drift
71% → 71% (0pp · 1 point)
Registry data
Apr 18, 2026
Peer-reviewed paper
Apr 18, 2026
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Source publication
A Randomized Trial of Intraarterial Treatment for Acute Ischemic Stroke
Olvert A. Berkhemer et al. · New England Journal of Medicine · 2015
· openalex W2139621750 · s2 93d703fd
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