All noemes
Trial · NCT01844505

Noeme · e6xdcxu2

Future
oncology

Forecast horizon — calibration-scored at resolution.

By 2028, 10-year survival data from CheckMate-067 will show a plateau ≥40% in the combination arm.

Your probability this resolves TRUE

Consensus 71%

0% (impossible)

50%

100% (certain)

25
50
75

Proper-scoring-rule preview

If TRUE: Brier 0.250 · log 0.69 · +8 rep
If FALSE: Brier 0.250 · log 0.69 · -1 rep
Kelly 25.0% ≈ 250 rep
vs. consensus: 0.15 bits

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Evidence stream

2 events · 1 snapshot

posterior drift

71% → 71% (0pp · 1 point)

posterior drift: 71% → 71%
neutral

Registry data

NCT01844505

Apr 18, 2026

supports

Peer-reviewed paper

+21pp

Expert reactions · 0

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Source publication

Overall Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma

Jedd D. Wolchok et al. · New England Journal of Medicine · 2017

5.3k citations
FWCI 229.8 · Landmark
OA · bronze
33 authors · 91% ORCID

· openalex W2753432434